Sentence examples for maintenance and synaptic from inspiring English sources

Here we examined synaptogenesis, synaptic maintenance and synaptic plasticity at cortical and sub-cortical excitatory projections to the LA in a model of RTT, Mecp2308/Y (KO) mice [16] and their Mecp2X/Y (WT) littermates.

To date the role of Mecp2 in the key phases of synaptic life – synaptogenesis, synaptic maintenance and synaptic plasticity - is still conflicting: A dramatic loss of excitatory synapses is observed in Mecp2-deficient primary neuronal cultures, but synaptic marker density appears to be normal in hippocampal slices of symptomatic RTT mice [3].

CACNA1F is important for the functional assembly and/or maintenance and synaptic functions of photoreceptor ribbon synapses.

BDNF is the most abundant neurotrophin in the brain, playing a critical role in growth, differentiation, maintenance, and synaptic plasticity.

Our results identify down-regulation of genes important for neuronal maintenance and synaptic transmission, but relative preservation of most constitutively expressed neuronal genes.

Therefore, RanBP9 may be involved in regulating neuritogenesis, synaptic maintenance, and synaptic plasticity changes via these pathways in addition to cofilin activation.

These targets, including peroxisome proliferator-activated receptor δ (PPAR- δ ), cyclin D-1, MITF, and FGF9 [ 1, 5, 20, 29, 33], have been implicated in the development of limbs, neural tube, forebrain, midbrain, and cerebellum, and in the maintenance of neurotransmission and synaptic plasticity [ 1, 5, 34, 35].

The glial origin of collagen or laminin highlights the close interrelationship between neurons and glial cells in establishment and maintenance of synaptic strength and plasticity.

The gene functions in the development and maintenance of synaptic networks and may be under the regulatory control of DISC1.

Although undoubtedly activity plays a critical part in the maintenance and refinement of synaptic connections, often via competitive mechanisms, evidence is building that it also drives the process of synapse formation itself.

Astroglial atrophy may indeed be the mechanism of early synaptic failure in neurodegeneration: reduced astroglial coverage impacts upon synaptic metabolic support, synaptic maintenance and neurotransmitter homoeostasis and turnover.