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Cancer-initiating cell (CIC) is critical in cancer development, maintenance and recurrence.
PGCCs may contribute to tumor maintenance and recurrence because PGCCs can be considered seed cells.
Cognitive models propose that biases in the processing of emotional information contribute to the onset, maintenance and recurrence of depression.
It has been argued that negative cognitive biases play an important role in the maintenance and recurrence of depressive symptoms and might be relevant for treatment outcome [ 14].
Later, a mouse model identified a putative endogenous GSC located at the apex of a cellular hierarchy that was involved in tumor maintenance and recurrence after chemotherapy.
As the next step, Chodosh and colleagues examined the role of the specific tumor suppressor gene p53 in oncogene-independent tumor maintenance and recurrence.
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The cancer stem cell theory suggests that a small population of progenitor cells with extensive self-renewal property determines the tumor initiation, maintenance, progression, and recurrence.
Experiments by Chodosh and colleagues illustrate the power of conditional transgenic mouse systems to investigate the impact of different initiating oncogenes on mammary oncogenesis, on oncogene-independent tumor maintenance, and on recurrence following initial regression.
Several terms that are employed in the literature which are related to the course of psychopathology include onset, maintenance, offset, relapse, and recurrence.
Conditional transgenic mouse models allow investigators to model possible therapeutic consequences of oncogene downregulation on the maintenance of malignancy and recurrence.
The current manuscript describes the key findings from a 48-week open prospective study of the effectiveness and tolerability of quetiapine monotherapy in a consecutively recruited series of adolescent patients meeting DSM-IV criteria for bipolar disorder and in whom maintenance treatment to prevent relapse and recurrence was clinically indicated.
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maintenance and frequency
maintenance and emergence
management and recurrence
maintenance and reactivation
maintenance and rehearsal
maintenance and distribution
maintenance and improvement
maintenance and desilting
maintenance and overhaul
maintenance and adjustment
maintenance and packing
maintenance and restoration
maintenance and training
maintenance and mortgage
maintenance and detoxification
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