Sentence examples for maintains tolerance from inspiring English sources

Communication between different immune cells of the intestinal mucosa acts as a rheostat that maintains tolerance to gut microbes.

Thus, DNA methylation maintains tolerance to self DNA, which can lead to impaired DNA methylation associated with lupus disease activity.

Regulatory T cells (Tregs) constitute a subpopulation of T cells, which modulates the immune system, maintains tolerance to self-antigens, and counteracts autoimmune disease [ 41].

Essentially, CD5 expression maintains tolerance in anergic B cells [ 28], inhibits early BCR signaling events [ 34], induces IL-10 secretion in B cells [ 29] and is associated with receptor editing/revision outside germinal centers [ 35].

CD5 protects from autoimmunity by several mechanisms that include the inhibition of BCR early signaling events [ 34], maintains tolerance in anergic B cells [ 28], and induces the secretion of IL-10 in B cells [ 29].

According to this theory, prior to industrialization, humans lived in a state of 'evolved dependence' with these microbes our 'old friends' that was critical for successful immunological functioning, specifically the development of an immunomodulatory response that maintains tolerance of self-antigens and abrogates autoimmune diseases (34).

The main function of DCs is to induce T-cell activation, polarization and expansion against invading pathogens while maintaining tolerance to self antigens (Steinman, 2007).

Regulatory T (Treg) cells establish and maintain tolerance to self-antigens and many foreign antigens, such as allergens, by suppressing effector T-cell proliferation and function.

Indeed, negative signalling by CD5 and CD22 in maintaining tolerance through recruitment of src-homology two domain-containing protein tyrosine phosphatase-1 has also been documented.

Maintaining tolerance within her craft is significant to how the artist completes her media.

By maintaining tolerance to opioids, such maintenance medications could also cut the death rate by 50percentt or more.