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The stimulatory effect of ACTH on gene expression is well documented and is thought to be a major mechanism by which ACTH maintains the functional and structural integrity of the gland.
Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor Buttonhead. eLife 3 e03502.
Hsp90 maintains the functional stability of neuronal proteins of aberrant capacity, thus allowing and sustaining the accumulation of toxic aggregates [ 95, 96].
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A yeast strain with its native mitochondrial DNA polymerase replaced by the human polymerase γ is viable and even maintains the functional mitochondrial genome essentially as efficiently as the wild type yeast (Qian et al. 2014).
This indicates that in wild type, SIR-2.1 maintains the functional excitability of the intromission and ejaculation circuit, possibly by slowing down the deteriorative events that accumulate during aging.
Similar(53)
Observations of localization of CSB protein in mitochondria and its role in the repair of mitochondrial oxidative DNA damage further add a new dimension to the multitude of complex cellular functions of CSB in maintaining the functional integrity of mitochondria.
We initially hypothesized that Pnt might function in parallel with Btd to maintain the functional identity of a type II neuroblast.
However, along the margins there are long, dense fringes of hairs that maintain the functional wing area.
Thus, MuSK and AChR together maintain the functional and structural integrity of the postsynaptic architecture and prevent axon growth.
Conservative exchanges (e.g. E → D) maintain the functional group of the targeted position, but due to other structural differences in the substitute residue, will affect the precise spatial placement and configuration of the functional group.
Related(17)
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