Sentence examples for maintains stem cell from inspiring English sources

Importantly, our data suggests that Oct4 maintains stem cell identity by targeting key regulatory genes which play critical roles in determining cell fate.

These observations suggest that UTX H3K27me3 demethylase maintains stem cell properties in multiple stem cell systems in different species.

ECM culture system maintains stem cell phenotypes, increases cell proliferative rate, and suppresses oxidative stress in BM-MSCs.

Additional questions include whether Lrig1 maintains stem cell quiescence and whether this activity contributes to its tumour suppressor function.

Wnt signaling controls stem behaviors, maintains stem cell habitus, and regulates cell migration and differentiation [ 5- 7].

Later in life, Hh signalling is however restricted, and, in adulthood, it presumably maintains stem cell populations and/or early progenitor cells.

SOX2, a member of the SRY-related HMG-box (SOX) family of transcription factors, stimulates the reprogramming of adult cells into induced pluripotent stem cells and maintains stem cell-like properties in cancer by complexing with other stem cell markers such as NANOG and OCT4 [ 9].

LIF is a member of the IL-6 cytokine family that maintains stem cells in an undifferentiated state and promotes stem cell renewal [ 23].

Despite their high potential to proliferate, the niche maintains stem cells in a quiescent and low metabolic state to prevent stem cell exhaustion [22].

Three transcription factors, Nanog, Oct4 and Sox2 form the core of a regulatory circuit, which maintains stem cells capacity for self-renewal and pluripotency.

In recent years, increasing evidences suggest that telomere length represents another important internal factor in maintaining stem cell pluripotency.