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Ectopic expression of tert in these cells does not result in telomere elongation (unlike in tert-immortalised NDFs) but merely maintains short telomere lengths, and the telomere fusions seen in primary NBSp70 cells are still prevalent, suggesting that NBNp70 has a dominant negative effect on aspects of telomere maintenance (Ranganathan et al. 2001; Siwicki et al. 2003).
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Non-phosphorylated Hsp-27, excluded from the leading edge of the lamellipodia, maintains short-branched actin molecules, whereas phosphorylated Hsp-27 at the base of the lamellipodia stabilises actin networks composed of long unbranched filaments (Pichon et al, 2004).
Our observations allude to isoform 1 being part of a larger macromolecular complex, or signaling pathway, that maintains shorter row stereocilia with active MET channels.
"It's more than trying to pick stocks that will go down, it's also having the strength to maintain short positions," said Bruce Ruehl, chief investment strategist at Tremont Advisers, a firm that tracks and consults on hedge funds.
The fabrication cycle for such NIL working templates with tunable feature sizes is maintained short and at a low cost.
The output data rate is constant (unlike for voltage-frequency converters) and the response time is maintained short without need of high modulator switching frequency.
Nitroxide-mediated radical polymerization (NMRP) of 4-vinylpyridine generates the rod-coil flexible chain which is maintained short to limit the insertion of insulating moieties in the additive structure.
In patients with AIED, hearing preservation with glucocorticoids is often only maintained short term [3], [6].
We think, however, that the best compromise is obtained when ground vegetation harbours abundant populations of invertebrates, which is rarely the case when the grass is either maintained short or is lacking completely over the whole surface [35].
These genes may play a key role in maintaining short root phenotypes of wild soybeans.
The reactivation of telomerase, restores chromosomal stability by maintaining short by stable telomeres and drives the immortal phenotype.
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