Sentence examples for maintains mitochondrial function from inspiring English sources
NAD+ has emerged as a vital oxidoreductase cofactor that regulates metabolism, activates sirtuins and maintains mitochondrial function by enhancing oxidative metabolism to promote healthy aging, and can extend lifespan in worms through the UPRmt stress response pathway.
Conversely, caloric restriction, which increases mitochondria biogenesis and maintains mitochondrial function, is associated with increased longevity [ 2].
Taken together, these data identify Clu as a mitochondrially-associated protein that plays a direct role in maintaining mitochondrial function and that binds TOM20, and support a role for Clu linking mitochondrial function to the PINK1-Park pathway.
We also demonstrate that Blm10 acts to maintain mitochondrial function.
In other terms, the failure of maintaining mitochondrial function through biogenesis may contribute to bad outcome.
These processes serve to maintain mitochondrial function and ensure optimal energy supply for the cell.
In this model, the neuroprotective capacity of Cr in the hypoxic perinatal brain is attributed to reduced lipid peroxidation and apoptosis, likely through maintained mitochondrial function [71].
Conclusion: The results indicate that preterm fetuses are more capable than term fetuses of maintaining mitochondrial function under conditions of transient intrauterine ischemia and suggest that oxygenderived free radicals may play a crucial role in the development of neonatal neurologic deficit.
We examined the critical roles played by the antioxidant, non-protein thiol, glutathione and related enzyme, glutaredoxin in maintaining mitochondrial function during excitotoxicity caused by β-N-oxalyl amino-l-alanine (l-BOAA), the causative factor of neurolathyrism, a motor neuron disease involving the pyramidal system.
In this context, autophagy is essential for synthesis of minimal essential proteins to maintain mitochondrial function during nitrogen starvation.
Indeed, there was partial activation of the mitochondrial biogenesis pathway involving NRF2α/GABP and its target genes TFAM, TFB1M and TFB2M yet clearly this failed to maintain mitochondrial function.
