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We observed that ds-DNA maintains its native structure and function during the formation of nanocomposite hydrogels.
The human 10th type III fibronectin (Fn3) is a small, 10-kDa protein domain that maintains its native fold without disulfide bonds.
Studies of the intrinsic fluorescence of the protein and of the extrinsic probe, 1-anilino-8-naphthalene-sulfonic acid, indicate that the protein mostly maintains its native structure in the conjugate.
Our data suggest that, by adjusting PrPC levels to wild type brain material, lysate of newly engineered and previously established animal cell lines can serve as an excellent substrate for PMCA, in which PrPC maintains its native states of subcellular localization, conformation, glycosylation, disulfide bridging, and glycosylphosphatidylinositol anchoring [40], [42], [53], [54].
These mutations do not compromise the overall structure or thermal stability of the ECD (Supplementary information, Figure S6A and S6B), and the mutant ECD maintains its native fold in the presence of liposomes (Supplementary information, Figure S6C).
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YbgF was denatured and might provide more epitopes to bind the specific antibodies in immonoblot assay, while it maintained its native structure and might provide less epitopes to bind the specific antibodies in the microarray assay.
Hep-gela-immobilized VEGF maintained its native biological activity.
The UV vis and FT-IR spectroscopic results demonstrate that the Mb in the composite film maintained its native structure.
Immobilized HGF promoted hepatocyte migration, thus indicating that L-ECM-immobilized HGF maintained its native biological activity.
A relatively more ordered structure of the enzyme at pH 8 and 9 as compared to that at pH 6 or 7 suggests a key role of the electrostatic interactions in maintaining its native tertiary structure.
The method works by performing a rapid computational screening of tens of thousand of mutations to identify those with the greatest impact on the solubility of the target protein while maintaining its native state and biological activity.
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maintains its haemodynamic
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maintains its hard-won
maintains its structural
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