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The initial peak is evoked by the release, and Ca2+ influx through VOCCs maintains elevated [Ca2+]i.
The stress-induced spike in RFRP3 initiates a long-lasting suppression of reproduction, well after the removal of the stressor, perhaps via positive feedback that maintains elevated RFRP3 levels or engages downstream suppressive targets.
In addition, cultivar IR66 maintains elevated expression levels of AM marker genes under both aerobic and anaerobic field conditions, suggesting high dependency of rice Pi uptake on the mycorrhizal pathway (Yang et al. 2012).
It would be important to study the sequence of these events in regards to RPE dysfunction to identify the key factors before a vicious cycle that maintains elevated VEGF levels is established.
DOI: http://dx.doi.org/10.7554/eLife.06376.007 10.7554/eLiFigure76.008 Figure 4 figure supplement 1. IL-6 maintains elevated cytosolic Ca2+ through its effect on the MMP and mitochondrial Ca2+.
cGMP activates PKG (McRobert et al., 2008) that in turn maintains elevated levels of cytosolic Ca2+ (see below) (Brochet et al., 2014), which regulates rounding up (i.e. increase in volume = water uptake?) of the cells and the expression of at least some translationally repressed surface proteins.
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In this case, a larger store of bone lead accumulated over a prolonged period (i.e., years) of exposure to elevated environmental lead levels could have maintained elevated blood lead levels that only very slowly decreased over time once the exposures were controlled.
Many Spanish and South American players maintain elevated rankings by plying their trade on the red stuff virtually all year round.
These species maintain elevated body temperatures at a relatively constant level by shuttling in and out of sunlight.
Based on theory, it is hypothesized that migrating contact areas can maintain elevated cartilage interstitial fluid pressurization, thus a low friction coefficient, indefinitely.
It was found that using reverse flow it was possible maintain elevated reactor temperatures which were capable of achieving high methane conversion of methane in air streams at methane concentrations as low as 0.19% by volume.
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