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Xian, L. et al. Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells.
These results suggest that CGRP signaling maintains bone mass both by directly stimulating stromal cell osteoblastic differentiation and by inhibiting RANKL induced NF-kappaB activation, osteoclastogenesis, and bone resorption.
If it is used in the early phase of menopause or immediately after ovariectomy, it maintains bone mass.
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Such drugs relieve symptoms of menopause, like hot flashes, and can also help maintain bone mass.
"In this study, we show that leptin gene therapy causes effective long-term weight loss while maintaining bone mass".
Before you reach 30 years of age, more bone is made than lost; after 30, this trend reverses, and calcium can help our bodies maintain bone mass.
One must keep in mind that the mechanisms responsible for bone formation to additional loading and maintaining bone mass with normal load, may not be the same as those for recovering bone mass after unloading39.
Given the importance of sex steroids for developing and maintaining bone mass, bone health is a matter of concern in daily management of these patients.
Load-induced fluid flow is a key factor in triggering bone modeling and remodeling processes that maintain bone mass and architecture.
Prime candidates have been a group of proteins called proteoglycans, which regulate the process of maintaining bone mass.
She led some of the first work on the role of weight-bearing exercise in building and maintaining bone mass and studied bisphosphonates as an osteoporosis treatment.
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