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The developed decellularization protocol was substantially reduced in processing time whilst maintaining tissue integrity.
The tough but yet resilient lamina propria provides resistance to tear and compression forces, thus maintaining tissue integrity that is crucial in such an active site that is constantly exposed to microorganisms.
Human tissues are remarkably adaptable and robust, harboring the collective ability to detect and respond to external stresses while maintaining tissue integrity.
This decrease in triiodothyronine production may be a beneficial adaptation to starvation and illness because it reduces the breakdown of protein and slows the use of nutrients for generating heat, thereby maintaining tissue integrity and conserving energy resources.
We propose that such a mechanism could be important in maintaining tissue integrity in normal adult tissues.
Desmosomes are intercellular junctions that provide strong intercellular links via the desmosome-intermediate filament complex and have a major function in maintaining tissue integrity [1].
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Vedula, S. R. K. et al. Epithelial bridges maintain tissue integrity during collective cell migration.
Under some circumstances, dying cells actively contract and cause their neighbors to rearrange and maintain tissue integrity.
The results of histopathology also showed 1 and 2 protected tissues (pancreas, liver and kidney) against peroxidation damage and maintained tissue integrity.
Epithelia that are faced with high degrees of environmental stress use virtually constant turnover rates of adult stem cells and/or their transiently amplifying progeny as a strategy to maintain tissue integrity, as seen in the skin [31] and lining of the gastrointestinal tract [32] where millions of cells are replaced daily.
This may provide a mechanism for stroma to maintain tissue integrity in adult epithelial tissue.
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