Sentence examples for maintaining the stem from inspiring English sources

To attempt to identify the full set of genes involved in maintaining the stem cell state ("stemness"), high-throughput technologies like microarrays [ 13], chromatin immuno-precipitation [ 6] and MPSS [ 14] have been used to compare gene expression profiles between ES cells and differentiating cells.

Therefore, the number of CB hematopoietic stem/progenitor cells (HSPCs) should be increased while maintaining the stem cell characteristics.

MaSCs are characterized by an asymmetric mode of division, generating one MaSCs and one progenitor per division, thus maintaining the stem cell pool.

In vivo the stem cell niche is an essential component in controlling and maintaining the stem cells' ability to survive and respond to injury.

Stem cells are in close contact with a special microenvironment, called the stem cell niche, which is crucial for maintaining the stem cell identity and the potential to self-renew (Li & Xie 2005).

Some of the earlier studies have pointed out the role of apoptosis cascade in maintaining the stem cell compartment [10], [11].

The underexpression of JAG2 and SOX10 was also unsurprising, because these genes, as previously discussed, are involved in promoting and maintaining the stem-like state.

Several groups have recently published data demonstrating this critical, and previously unknown, role of hypoxia in maintaining the stem-like fraction of cancer cells (Jogi et al, 2002; Heddleston et al, 2009; McCord et al, 2009).

The proteins these genes encode are involved, as part of a highly coordinated transcriptional program, in maintaining the stem-like state and in activating the epithelial-to-mesenchymal transition [ 21, 22].

We observed that HGF was closely associated with AUA-1-positive CRC metastases, situated adjacent to myofibroblasts, which strongly suggests that HGF also has an important role in maintaining the stem-like phenotype of CRC stem cells in the metastatic niche.

One remains in the stem cell state to maintain the stem cell population, a process called self-renewal.