Therefore, to maintain the same sequence size, we decided to carry out the alignment with 1023 nucleotides of the DENV-3 E gene.
The OTUs corresponding to very similar orthologs within a single lineage were omitted so that the final dataset containing 246 OTUs maintained the same sequence diversity and taxon distribution as the original.
Isolates belonging to single bacterial species generally maintain the same sequence elements but show variation in the number of repeat units through the activity of a strand-slippage mechanism introduced by DNA polymerase during replication [ 7- 9].
In each simulated run, every empirical SNP in the 3′-UTRs was shuffled to a random position maintaining the same trinucleotide sequence (i.e., the SNP position itself and the nucleotides immediately before and after).
This redundancy represents a key step in modulating the efficiency and accuracy of protein production while maintaining the same amino acid sequence of the protein.
Importantly, if you change the topology, while maintaining the same distance between two sequences, or even maintaining the same total tree length, you generally change the likelihood of the model (i.e., you change the probability of the sequences).
Orthologous genes are defined as homologous genes, which originated from a common ancestor, and subsequently diverged from the original sequence, usually maintaining the same function.
The permutation operator with local learning or random shuffling is applied to the same design individual to improve the fitness for layer sequence dependent criterion, while maintaining the same performance for layer combination dependent criterion.
Low numbers of true mutations were found based on a conservative interpretation that any sequence that does not maintain the same baseline sequence (rCRS or rCRS with changes) as the original amplified bulk sample (this predominant sequence is denoted as HV1∞) is likely to be an artifact due to sample contamination.
By simulation, we randomized the nucleotide sequences of human intron-exon database but maintaining the same exon-intron structure and nucleotide compositions (see Methods).
