Sentence examples for maintaining the differentiation from inspiring English sources

Thus, minimizing the number of involved factors, while maintaining the differentiation efficiency, provides less costly and controllable conditions.

Our previous in vitro studies have clarified that FGF-2 facilitates proliferation while maintaining the differentiation of human periodontal ligament cells (HPDLs).

Yet, when cell death is inhibited, DKO myotubes can differentiate as efficiently as Rb mutant or control cultures, demonstrating that neither factor is required for stimulating or maintaining the differentiation program.

It may thus have essential functions in maintaining the differentiation of the follicular epithelium.

We propose that modulation of transcription levels by NuRD is key to maintaining the differentiation responsiveness of pluripotent cells.

Wang et al.'s findings have revealed an important role for Wnt signaling in maintaining the differentiation niche.

Kouros-Mehr, H., Slorach, E. M., Sternlicht, M. D. & Werb, Z. GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland.

Extracellular matrix (ECM) derived from mesenchymal stem cells (MSCs) has recently been shown to be able to maintain the differentiation potential of MSCs during culture expansion and to restore the activities of aging MSCs, suggesting that MSC ECM (MECM) may be a suitable culture substrate to enhance the bioactivity of biomaterial scaffolds for MSCs.

Smooth muscle cells (SMCs) express a unique set of microRNAs (miRNAs) which regulate and maintain the differentiation state of SMCs.

These data suggest that a single allele of Smad5 was sufficient to maintain the differentiation program of chondrocytes, while per previous report, complete loss of Smad1 and Smad 5 in cartilage led to a severe chondrodysplasia with altered chondrocyte differentiation [13].

For these traits we have maintained the differentiation among positive scores with the supposition that the use of the scale by the BVA/KC panel of experts embodies confidence in diagnosis as well as degree and that ignoring scoring categories may 'coarsen' the scale of analysis.