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In addition to its role in maintaining structural tissue integrity, E-cadherin has also been suggested as an important modulator of cell signaling via interactions with its cytoplasmic binding partners, catenins, as well as with growth factor receptors.
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The ECM, responsible for maintaining structural and functional properties of the tissue, is synthesized entirely by cells within the tissue exhibiting both fibroblastic and chondrocytic characteristics, and referred to herein as meniscal fibrochondrocytes (MFCs).
Synthetic elastomeric scaffolds may be useful for a range of tissues due to their ability to support mechanical deformations while maintaining structural integrity, similar to native elastic tissues, such as blood vessels and cardiac muscle [6].
In situations where regeneration fails, FAPs persist and generate fibrous/fatty tissue that, while maintaining structural integrity, hinders function and subsequent regeneration [ 33, 34].
Thus, the iron finger is required for maintaining structural integrity of the TibC dodecamer.
We believe this novel vimentin-linked N-cadherin/γ-catenin junction provides the tensile strength necessary to establish and maintain structural integrity in tissues that lack desmosomes.
In the adult, the main function of fibroblasts, prototypical mesenchymal cells that exist in many tissues, is to maintain structural integrity by secreting extracellular matrix (ECM).
Apoptosis is the major type of cell death involved in development and tissue homeostasis to build up and maintain structural and functional organs.
Hyaluronan is rapidly produced upon tissue injury to provide a temporary matrix to maintain structural integrity, but upon its fragmentation size-specific fragments of hyaluronan can be proinflammatory, and clearance of hyaluronan is required for resolution of inflammation.
To form tissues with uniform cell distribution and extracellular matrix arrangement is of great relevance to obtain the desirable function and maintain structural integrity.
Fittings found to be cracked were being replaced following the inspections to maintain structural integrity.
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