Sentence examples similar to maintaining stem integrity from inspiring English sources

These cellular components are essential in maintaining the integrity of stem cells.

Piwi and argonaute proteins are essential for maintaining genome integrity in stem cells in a process referred to as piwi-interacting RNA (piRNA) pathway; in short they repress the mobilization of transposable elements (TEs).

However, there is still considerable controversy regarding how such a nonrandom segregation mechanism might work with respect to maintaining genomic integrity in the stem cell (Lansdorp 2007).

In the epidermis, Rac 1 was found not to be crucial for maintaining epithelial integrity but for stem cell differentiation, presumably via negative regulation of c-Myc expression (Benitah et al. 2005; Chrostek et al. 2006).

Maintaining genomic integrity is vital for the stem cell because mutations will severely compromise all derived cell lineages and their progenies.

In this review, we discuss the causal link between stem cell dysfunction and DNA damage accrual, different strategies how stem cells maintain genome integrity, and how these processes are affected during ageing.

Here we discuss dietary impact on fertility, and highlight a recent report on the activity of a nuclear receptor that protects against dietary metabolites to maintain germline stem cell integrity and reproduction.

An understanding of the function of prostate stem cells in the lineage-associated differentiation responsible for maintaining tissue integrity has potential application to prostate regeneration and tumorigenesis.

Recent study from Dr. Brigitta Stockinger's group55 also suggests AhR protects from inflammatory damage by maintaining intestinal stem cell homeostasis and barrier integrity supporting our observations that activation of AhR enhances the barrier integrity.

Originated from the haematopoietic stem cells, the endothelial progenitor cells (EPC) are believed to participate in repairing the damaged endothelium and maintaining the integrity of vascular lining [ 44].

Metidji, A. et al. The environmental sensor AHR protects from inflammatory damage by maintaining intestinal stem cell homeostasis and barrier integrity.