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Further adjusting the model with log of individual AMH values (representative of ovarian reserve) caused the FMR1 factor, however, to lose significance, while maintaining significance of race/ethnicity.
Among 55 loci previously associated with DN, three showed suggestive associations with SDR in our study without maintaining significance after correction for multiple testing.
Coumesterol at a concentration of 10-8 M caused a more sustained activation of ERK, maintaining significance at 10 to 30 min, also similar to previous observations [ 26].
Only SNPs at the PLXDC2 locus on chromosome ten showed nominal association in the same direction as the original study without maintaining significance after correction for the effective number of tests (P > 0.0015 for 34 DR loci).
Regression analyses were used to examine the degree of association between baseline vitamin D levels and demographic characteristics, fracture type, surgical procedure, and cognitive status - first at the univariate level, followed by multivariate modelling to determine those variables maintaining significance while controlling for all others.
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In the gene expression data, the continuous form of the TP53 variable was not significant while the WGCNA* high mortality group maintained significance at the 0.05 level for all 8 of the Pawitan 2005 models.
All significant control variables in Model M1 continued to maintain significance in Model M2.
In addition, the interaction term of traffic modified by low wind speeds remained significant in several cases where the main effect of traffic did not maintain significance.
In high-risk offspring with a lifetime mood disorder, a comorbid lifetime history of a SUD also influenced stability of daily secretion (AUC), where cortisol levels decreased over time among those with a prior SUD and remained stable among those without a SUD; however, the interaction pertaining to SUD did not maintain significance after adjustment for multiple comparisons.
Because of these effects, we tested whether the parametric relationship between T, generosity and punishment maintained significance controlling for the order of Androgel® administration.
A two-tailed, Fisher's Exact Test indicated that the probability of such a result is highly unlikely to be due to chance (n = 9, P = 0.0013) and, indeed, this result maintained significance under a Bonferroni correction for 17 tests.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com