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Neumann and Gill [ 26] found that their continent subjects were unable to contract the pelvic floor effectively, while maintaining relaxation of the transversus abdominis and internal oblique muscles.
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These mechanosensitive potassium channels are thought to help maintain relaxation of myocytes in visceral hollow organs by hyperpolarizing the membrane and have been found to regulate responses to nitrergic stimulation [18].
The closed-loop infusion is a very sensitive technique in providing stable surgical operating conditions, while diffusing minimal amount of drug to maintain relaxation at a given level [ 3].
Pregnancy coordinately alters the contractile properties of both vascular and uterine smooth muscles reducing systemic blood pressure and maintaining uterine relaxation.
Although acute inotropic activation of these pathways helps increase the Ca transient while maintaining efficient relaxation, chronic activation may lead to Ca overload, diastolic dysfunction, and arrhythmias.
Rocuronium was also given to maintain muscle relaxation.
Particular care was devoted to maintain full relaxation of the examined muscles and trials contaminated by involuntary movement or muscle activity were discarded from further analysis (Fig. 2).
Rocuronium 0.6 mg/kgBW was used to facilitate tracheal intubation and maintain muscle relaxation.
Before the uterine incision deep inhalational anesthesia with sevoflurane is used to maintain uterine relaxation and preserve uteroplacental circulation and fetal gas exchange.
A lidocaine drip (2 mg/min) was initiated to prevent arrhythmias, and intravenous injection of vecuronium bromide (5 mg) was administered to maintain muscle relaxation.
Tuzcu et al. described a male patient with a suspicious spinal mass who was difficult to intubate even after the administration of 100 mg succinylcholine, a 50 mg loading dose of rocuronium, and a 5 μg/kg/min infusion used to maintain muscle relaxation [ 14].
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