Sentence examples for maintaining quiescence from inspiring English sources

Thus, the regulatory mechanisms maintaining quiescence are robust even to complete loss of conserved transcription factor binding events.

Common among these is that self-renewing and multi-potent long-term HSCs exist throughout life, maintaining quiescence relative to other hematopoietic cells [1].

Using rDNA technology, it may be possible to engineer rAH derivatives that have stronger anti-HIV activity while maintaining quiescence in the toxicological aspects.

This report of a regulated increase in both expression as well as channel function supports our hypothesis that TREK-1 channels are important in maintaining quiescence during pregnancy and that channel expression and or activation may be dysregulated in spontaneous pre-term labor.

Further, alveolar epithelial cells from p21−/− mice have an increased proliferation rate and lung tumorigenesis is enhanced in adult mice heterozygous for a null mutation in TGF-β1, supporting a role for this pathway in maintaining quiescence in the normal respiratory epithelium in vivo [29] [31].

Consistent with a global role in maintaining quiescence, E2F4 has been shown to bind to and regulate a set of proliferation and cell cycle related targets in a number of ex vivo human cell lines, including glioblastoma [8], [13], fibroblast [14], and osteoblasts [15].

Yamada, T., Park, C. S., Burns, A., Nakada, D. & Lacorazza, H. D. The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells.

Bjornson, C. R. et al. Notch signaling is necessary to maintain quiescence in adult muscle stem cells.

We systematically reviewed the effectiveness of tocolytics to stop uterine contractions (first-line therapy) or maintain quiescence (maintenance therapy).

Here we show that adult muscle satellite (stem) cells in mice produce extracellular matrix collagens to maintain quiescence in a cell-autonomous manner.

Here, through the use of a physiomimetic system that recapitulates the mechanical microenvironment found within healthy and fibrotic pancreas, we show that matrices mirroring rigidities found within fibrotic pancreas activate PSCs, whilst matrices resembling healthy pancreas induce and maintain quiescence in previously activated PSCs.