Sentence examples for maintaining protein functionality from inspiring English sources
Since mutations and other evolutionary changes have led to modifications in the coding sequences within the requirements of maintaining protein functionality, the introns may have a role to play such as maintaining the structure of base arrangements so that the restrictions implied by the equations 16, 17 can continue to apply.
In contrast, the low Ka/ Ks ratios for the 5-exon/4-intron GTLP genes (e.g., 0 to <0.01) indicate strong purifying selection pressure to conserve the encoded amino acid sequence in order to maintain protein functionality.
The selective pressure to maintain protein size therefore does not appear to be a selective pressure for pleiotrophy/multi-functionality within individual proteins.
Out of 615 exonic variants, 427 were new, and 68% of them did not affect protein functionality by maintaining the reading frame or occurring within non-protein coding genes.
Thus protein functionality may be maintained despite mutation over many generations in the absence of selection, while the cells live in an environment that relieves them of the necessity to perform oxidative phosphorylation or other aerobic mitochondrial activities.
In general, amino acids with similar physicochemical properties may substitute each other while maintaining the protein's functionality.
Moreover, functional proteins maintain their functionality much better on the S-layer protein matrix in comparison when being directly attached (immobilized) to solid supports.
We propose this as one of the biological mechanisms that regulate extracellular protein functionality.
Protein-protein interaction (PPI) networks are frequently used to map protein functionality [ 1- 5].
However, one of the most important aspects of these conformations is maintaining the functionality of the immobilized protein, which is determined by the choice of lipids and surfactants employed in the reconstitutions.
Interactions between acidic residues on surface and hydrated salt ions not only prevent protein aggregation (5) but also maintain the functionality of the protein.
