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Here we dissect the relationship of two proteasome-associated polyubiquitin-binding proteins, Rpn10 and Dsk2, and demonstrate how Rpn10 filters Dsk2 interactions, maintaining proper function of the ubiquitin-proteasome system.
Consistent with this hypothesis, it has been noted in earlier studies that a homeostatic distribution of mitochondria in peripheral regions of neurons in particular, axons and dendrites is critical for maintaining proper function [1], [45].
These data confirmed that Baf250a is required for maintaining proper function of the SAN.
For the first time, we elucidate a repressive epigenetic pathway maintaining proper function of the SAN.
A critical role of Baf250a/Tbx3 genetic pathway in maintaining proper function of pacemaking cells gains further supports from several genome-wide association studies.
The activation of miR-223 by CEBPA can trigger neutrophil differentiation and is necessary for maintaining proper function of mature neutrophils (Fazi et al, 2005, 2007; Johnnidis et al, 2008).
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If mechanical tension is removed, those tissues undergo atrophy, indicating the important role of mechanical signals for maintaining proper functioning of the organism [ 84].
Repairable equipment requires preventive maintenance (PM) to maintain proper function.
Joints are thought to be designed to operate within a "physiological window" to maintain proper function and allow for positive adaptations [12].
Thus the critical function of A-type lamin C proteins in Drosophila musculature is to maintain proper function and morphology of tendon cells.
In order to maintain proper function of the battery pack, the heat dissipation around battery cells should be deeply investigated and well controlled.
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maintaining proper copper
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maintaining normal function
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maintaining proper homeostasis
maintaining proper form
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maintaining proper positioning
maintaining proper length
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maintaining synaptic function
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