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Intracellular transport is essential for maintaining proper cellular function in most eukaryotic cells, with perturbations in active transport resulting in several types of disease.
Plasmalogens have been found to play an important role in maintaining proper cellular membrane functioning and in preventing oxidative damage [26], [32].
This suggests a role for KLLN in maintaining proper cellular proliferation.
The transcription factor hypoxia-inducible factor (HIF -1 represents one important element in maintaining proper cellular functions under sucHIF -1xic conditions [ 1].
The architecture of the extracellular space is important for maintaining proper cellular function; loss of tissue architecture is a defining characteristic of epithelial cancers.
GSH is essential for maintaining proper cellular redox status and protecting against toxicity and other stress conditions that may occur in neurons (11, 15).
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The system may be protecting these important transcription factors from gene expression fluctuations in order to maintain proper cellular functions during DR, leading to increased life span.
Key examples are the increased expression of shock proteins to maintain proper cellular metabolism as a response to heat stress (Sorensen et al. 2003; Bergmann et al. 2010; Csaszar et al. 2010).
Further endeavors are needed to address how to maintain proper cellular autophagy level, as well as the safety issues regarding long-term application of autophagy-related drugs to PD subjects.
As a positive regulator of apoptosis in mammals, AIFs function in apoptotic and redox signalling: which enhances mitochondrial bioenergetics and complex I activity/assembly to help maintain proper cellular redox homeostasis in mitochondria and forms a chromatin degrading complex with other proteins in the nucleus [ 29].
Proper regulation of gene expression is essential for cellular viability, and the integrity of chromatin is a fundamental factor in maintaining proper gene regulation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com