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Besides cortisol, prolactin might also be important in maintaining normal immune response in stress states.
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Consistent with normal immune homeostasis by lifetime exposure to a soluble TGF-β antagonist (Yang et al, 2002), treatment with EW-7197 for 8 weeks maintained normal immune homeostasis (Fig 7A D).
Furthermore, cIAP-2 knockout macrophages were reported to be highly susceptible to apoptosis in an LPS-induced proinflammatory environment, indicating that cIAP-2 is a critical factor in maintaining normal innate immune responses [24].
Ubc9 controls the "set point" by maintaining normal levels of IκB/Cactus protein in immune tissues (Paddibhatla et al., 2010).
Thus, CD-like ileitis develops with selective deletion in adult mice, illustrating that SHIP expression is required to maintain normal mucosal immune homeostasis and regulation in the adult ileum.
Magnesium helps in maintaining normal nerve and muscle function, a healthy immune system and helps bones remain strong.
Vitamin A is an important micronutrient for maintaining normal growth, and is essential for a well-functioning immune system and visual and reproductive functions.
Maintaining normal social contact is important to well-being.
The microbiome stimulates the early maturation of the immune systems in infants while maintaining the normal immune functions of adults; meanwhile, many of the immune-related diseases are primarily caused by dysbiosis in the microbiome (Kamada et al., 2013).
Therefore, these chemokines possess the capability of maintaining the normal immune function and the protection against infectious agents and other external toxicants [56], [57].
IL-10 has an important role in maintaining the normal immune state.
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