Sentence examples for maintaining neuronal integrity from inspiring English sources
Although the BBB is crucial in regulating CNS homeostasis, and essential for maintaining neuronal integrity, it limits drug delivery to the CNS.
It suggests that Pn is essential for maintaining neuronal integrity besides involvement in eye pigment biosynthesis.
4 In neurons, MAPT binds to axonal microtubules, promotes microtubule assembly and stabilization, and plays a role in maintaining neuronal integrity and axonal transport.
This review summarizes the recent literature on neuronal aging in C. elegans, including our own findings, which indicate a role for protein with tau-like repeats (PTL-1), the homolog of mammalian tau and MAP2/4, in maintaining neuronal integrity during aging.
The four virulence-associated factors maintained neuronal integrity while triggering a [Ca2+]i increase in cerebellar neurones, which was followed by the release of glutamate.
Parkin has been shown to maintain neuronal integrity under various stressful conditions, including mitochondrial stress, excitotoxicity and ER stress [16], [17], [18].
Furthermore, using Purkinje cells as a model system to analyze the role of miRNAs in postmitotic, differentiated neurons, the inactivation of Dicer enzyme leads to rapid loss of cell-specific miRNAs and the slow degeneration of the Purkinje cells leading to ataxia and severe cerebellar dysfunction, suggesting miRNAs are required to maintain neuronal integrity [22].
The autosomal recessive models have uncovered the importance of mitochondrial QC and transport for maintaining neuronal function and integrity.
These observations suggest that MUL1 acts in parallel to the PINK1/parkin pathway to ensure mitochondrial integrity and function, thus maintaining neuronal health in primary cortical neurons.
These cells function primarily to survey the microenvironment for pathogens, maintain neuronal synaptic integrity, and kill exogenous pathogens.
As well, they are critical in maintaining the neuronal integrity of the brain, particularly the cerebral hemispheres [ 1- 10].
