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Genes integral for maintaining network integrity and controlling information flow are dynamically changing as the breast tumor coexpression network adapts to perturbation by the drug letrozole.
Nodes that have many links, called hubs, and those that lie in well-traveled paths, called bottlenecks, are integral for maintaining network integrity and paths of information-flow [ 4].
As highly connected nodes hubs play an integral role in maintaining network integrity and in mass information transfer.
These findings indicated that the modular connectors were crucial for the global coordination of information flow in the brain functional networks, which was in accordance with a previous study in the mammalian brain networks showing the existence of connector hubs and their importance for maintaining network integrity [65].
Accordingly, key genes that are maintaining network integrity and modulating information-flow change over time in the presence of the drug.
Highly connected and highly centered nodes are likely to play crucial roles in maintaining network integrity and controlling information flow throughout the plant immune system.
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A promising approach is to use biological networks to prioritize targets based on their relative positions to one another, a property that affects their ability to maintain network integrity and propagate information-flow.
As an enduring hub, CAV1 plays a central role in maintaining coexpression network integrity.
In the interests of maintaining maximal network integrity compatible with the separation, all such superfluous externals need to be reincorporated before finalising the subnets.
Partitioning is performed progressively and the interactive visual matrix presentation used allows the user considerable control over the process, while incorporating special strategies to maintain the network integrity and minimise the information loss due to partitioning.
However, this pattern does not rule out an active role of selection at the lower scale: links need to be introduced and removed at appropriate rates so that the network integrity is maintained.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com