Sentence examples for maintaining mitochondrial numbers from inspiring English sources

In eukaryotes, mitochondrial fusion-fission is important for maintaining mitochondrial numbers and morphology, and plays a critical role in sustaining functional mitochondria [32,33].

Moreover, the protein supercomplex 5 in the IMM of WT cells is a non-respiratory supercomplex composed of many molecules of Yme2p, an integral IMM protein with a role in maintaining mitochondrial nucleoid structure and number.

Mice lacking functional HtrA2 and cells derived from them show impaired mitochondrial function, and Drosophila lacking HtrA2 were found to exhibit increased numbers of defective mitochondria, all suggesting a crucial role for HtrA2 in maintaining mitochondrial physiology.

Cardiolipin (CL) has a critical role in maintaining mitochondrial inner membrane structure.

In the case of Parkinson's disease, many signposts point to disruption of mitochondrial health as a major factor and thus the importance of mitochondrial transport in maintaining mitochondrial health takes on great relevance.

Mitochondrial dynamics refers to the processes maintaining mitochondrial homeostasis, including mitochondrial fission, fusion, transport, biogenesis, and mitophagy.

This process, mitophagy, is considered crucial for maintaining mitochondrial integrity and suppressing Parkinsonism.

In other terms, the failure of maintaining mitochondrial function through biogenesis may contribute to bad outcome.

Our hypothesis is that cellular mechanisms maintaining mitochondrial function must be protected in order to prevent MODS.

Mammalian mitochondria have their own NAD biosynthetic machinery which plays a key role in maintaining mitochondrial NAD pool [13, 115].

This report highlights a novel function of PINK1 in mitochondrial biogenesis and a role in maintaining mitochondrial ETC activity.