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Our neocortical differentiation system preserves hPSC aggregates, maintaining intercellular communication and the multi-lineage differentiation ability of hPSCs, while employing trophic factors specifically involved in neocortical development.
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In the absence of Wnt/β-catenin pathway activation, β-catenin is important in maintaining epithelial intercellular communication [35] and is therefore found in normal mammary duct epithelial cells, typically showing a diffuse cytoplasmic distribution or localization to the basolateral plasma membrane in glands from either BK5.ATF3 transgenic (Figure 1A) or non-transgenic (Figure 1B) animals.
Apart from tumour cells, the tumour microenvironment is a crucial source of angiogenic cytokines, proteases and vascular stimulating factors, which are important to maintain the intercellular communication (Kalluri and Zeisberg, 2006; Orimo and Weinberg, 2006).
Alternatively, taurine could help maintain gap junctional intercellular communication required for cell fusion, as has been shown in liver.
Our results reveal inextinguishable hair-cell regeneration in the lateral line, and suggest that the neuromast epithelium is formed by plastic territories that are maintained by continuous intercellular communication.
Background/Aims: Carbonic anhydrase isoenzyme IX (MN/CA IX) is a transmembrane protein with a suggested function in maintaining the acid base balance and intercellular communication.
Chemokines and their receptors orchestrate the intercellular communication required to maintain the complex architecture of immune compartments in the intestine at multiple levels.
The endocytic uptake of proteins and lipids is the driving force that establishes and maintains cellular polarity, but also allows for intercellular communication and facilitates interactions with the environment [ 1, 2].
Gap junction-mediated intercellular communication (GJIC) is critical for maintaining integral cellular processes including differentiation and growth control.
Moreover, they exert an inhibition of intercellular communication.
Intercellular communication in many organs is maintained via GJIC.
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