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In general, therefore, the data showed that p56Lck, and thus the TCR signal, is more important for maintaining gene expression than for repressing it.
Epigenetic regulation is necessary for maintaining gene expression patterns in multicellular organisms.
These results suggest that paralogous CNSs are conserved mainly because of maintaining gene expression in the vertebrate brain.
The importance of epigenetic regulation in maintaining gene expression and, therefore, cell fate determination is well established.
Published online: February 9 , 2012Polycomb-group (PcG) repressor proteins play a key role in establishing and maintaining gene expression patterns during cellular differentiation and development.
DNA methylation, as an important and long-term stable epigenetic mechanism, defines cell fate by maintaining gene expression patterns and stabilizing genetic mobile elements.
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Finally, in vivo experiments showed that the biodegradable HES markedly reduced the non-specific lung transcription of the polyplexes, but maintained gene expression in the tumor, contrary to the non-degradable HES and PEG controls, which reduced both tumor and lung expression.
Polycomb group (PcG) proteins are essential to maintain gene expression patterns during development.
Polycomb group (PcG) proteins maintain gene expression patterns during development in animals and plants by establishing a cellular memory system for transcriptional repression [1].
In order to favour biologically maintained gene expression changes, we filtered the data to identify genes that were significantly regulated (p≤0.05) in each of the two cohorts, rather than relying on overall statistical significance in the study.
As described below, we expect that weak selection to maintain gene expression stability may result in positive selection on certain compensatory regulatory changes in spite of the fact that most novel alleles are likely to be deleterious.
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managing gene expression
sustaining gene expression
conservation gene expression
update gene expression
maintaining gene overexpression
maintaining gene absence
maintaining protein expression
maintaining gene silencing
maintaining gene functionality
maintaining gene balance
maintaining gene repression
maintaining gene function
maintaining gene flow
maintaining gene copy
maintaining gene nomenclature
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