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Previous studies have demonstrated that acinar cells undergoing pancreatitis-induced metaplasia upregulate Pdx1, a transcription factor normally expressed in progenitor cells, while maintaining expression of Ptf1a, a master regulator of acinar cell identity (Jensen et al., 2005; Molero et al., 2007).
Somatic cells can be reprogrammed to a pluripotent-stem-cell state by maintaining expression of specific combinations of proteins through several rounds of cell division [1] [7].
We propose that BMP suppresses differentiation by maintaining expression of Cdh1.
Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin.
hESCs cultured in this system could be passaged onto fresh microcarriers and expanded further while maintaining expression of pluripotency markers.
At 1 week after multiple low-dose STZ administrations, pancreatic β-cells showed impaired insulin expression, while maintaining expression of nuclear Nkx6.1.
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As much as Ms. Franganillo and her co-choreographer, Oscar Martinez Pey, might have liked to suggest the Barthes-like subtleties of love's discourse, the dancers brought little emotional complexity to their performance, simply maintaining expressions of fraught intensity throughout.
Adult SCs maintain expression of OCT4, and because CSCs express this gene, this suggests tumor cells are derived from normal SCs (Tai et al. 2005).
Mase et al. found that many miRNAs in the let-7 family are expressed in human ovarian granulosa KGN cells, which maintain expression of FSH receptors.
In addition, they maintained expression of CD105, CD73, and CD90.
Undifferentiated 5T4-GFP ES cells lack EGFP and maintain expression of the pluripotent markers OCT-4 and NANOG.
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