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Vitamin A is essential in maintaining epithelial cells, preventing atrophy and keratinization of epithelial tissues.
Of the sixty two, cell differentiation genes identified in LEC only five were upregulated (table 2) these were involved in maintaining epithelial cells in an undifferentiated state.
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Regulation of cholangiocyte survival is crucial for maintaining epithelial cell integrity in the biliary tract.
This further suggests that the BMP pathway is important in maintaining epithelial cell homeostasis.
This suggests that normally Dlc1 plays a role in maintaining epithelial cell polarity and that it is haploinsufficient.
Villus epithelial cells also displayed clear increases in the expression of several growth and differentiation associated genes, and genes involved in establishing and maintaining epithelial cell polarity, as compared to the levels observed in crypt epithelial cells.
We investigated in silico the expression of 369 genes experimentally recognized as involved in establishing and maintaining epithelial cell identity and mammary gland remodeling, in HELUs or ADHs with respect to the corresponding patient-matched normal tissue.
In particular, gene expression profiling and ChIP-seq studies enabled us to demonstrate that Ezh2 plays a novel role in maintaining epithelial cell lineage specification by depositing H3K27me3 repressive marks at the promoters of basal genes in the epithelium.
PAR1b is one of four structurally related members of the PAR1 family of kinases, and has an essential role in maintaining epithelial cell polarity by phosphorylating microtubule-associated proteins (MAPs), and destabilizing microtubules to permit the asymmetric distribution of molecules required for cells to maintain polarity [ 32, 69- 71].
Another study noted decreased protein levels of ADH1B in breast tumors [24], postulating the inability to oxidize the hydroxyl group of retinol blocks the production of retinoic acid, a molecule that helps maintain epithelial cells in their differentiated state.
It acts a critical role in embryonic development and maintains epithelial cells throughout life [ 20].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com