Sentence examples for maintaining endothelial cell from inspiring English sources

It has became clear, however, that during the angiogenesis process the αvβ3 integrin plays a fundamental role in maintaining endothelial cell viability.

VE-cadherin-mediated cell-cell adhesion and integrin-mediated cell-matrix adhesion are essential for maintaining endothelial cell monolayer tightness [36], [37].

BIRC2 has been demonstrated to be essential for maintaining endothelial cell survival and vascular integrity in zebrafish by activating the formation of the TNF receptor complex I as well as promoting the degradation of IκB, upon which NF-κB is released and translocates into the nucleus where it activates pro-survival genes in endothelial cells [47].

Notably, autocrine VEGF-A-induced signal transduction is considered essential for maintaining endothelial cell survival [ 76].

That CBS is important for maintaining endothelial cell homeostasis is supported by findings showing that reduction in CBS expression induces premature senescence in HUVECs (Albertini et al. 2012).

JAM-A is known to act by inducing and maintaining endothelial cell junction organization (Ebnet et al, 2004; Nourshargh et al, 2010).

In general, TJs seal the interendothelial cleft to form a continuous blood vessel, while the AJs are important for initiating and maintaining endothelial cell-cell contact [ 58, 59].

It has been reported that VEGFR2 is crucial for maintaining endothelial cells development and that homozygous VEGFR2 mutants were not viable.

Cardiac endothelial cells maintain endothelial cell function such as vascular tube formation and acetylated-LDL uptake in vitro.

Furthermore, sphingosine-1-phosphate maintains endothelial cell integrity and inhibits lymphocyte extravasations via the sphingosine-1-phospate receptor.

Recently, Terasaka et al (Terasaka et al, 2008) identified a novel mechanism whereby HDL may maintain endothelial cell NO production and availability in mice fed a high-cholesterol diet.