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The aim of our study was to define the effect of knocking down Sox2 in developing preimplantation mouse embryos, in order to uncover early functions in maintaining developmental potential of early mouse embryos and marking the pluripotent lineage [53].
These data suggest that growth factor signalling through PI 3,4,5 P3, and by extension PKB, does not play a significant role in normal skeletal muscle hypertrophy but may play a role in maintaining developmental growth and insulin sensitivity.
Together, our results support a role for OCRL1 in maintaining developmental signalling pathways downstream of clathrin-mediated membrane traffic.
Insects that enter into photoperiodic diapause are expected to display patterns of expression specific to the mechanisms maintaining developmental arrest.
Certainly, the correct nutritional cues are necessary for normal progression of the oogenic cycle and so may also have an important role in maintaining developmental arrest.
Symmetrical breast development may well be an indicator of an individual's ability to tolerate 'disruptive' hormonal variation whilst maintaining developmental stability.
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The results show that A. cytisoides maintains developmental stability at the expense of productivity.
Only about half of the oocytes maintained developmental potential after exposure to anisotonic solutions compared to untreated controls.
To enhance the applicability of the cold-storage technique, prolonging the time to maintain developmental ability of the embryos is required.
Heterozygous genotypes maintain developmental homeostasis, which allows them to adjust to environmental changes.
Within the context of ESCs, an important function of Cobra1 may be to help maintain developmental genes in a repressed yet poised transcriptional state.
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