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These results suggest that Ga5DH is involved in maintaining correct cell shape and in cell division.
Normal epithelial cells produce S1P to trigger their extrusion and death once they become too crowded, simultaneously maintaining correct cell density and barrier function.
The CTNNB1-independent Wnt pathway comprises two segments, namely the planar cell polarity and calcium signaling segments, and its proper regulation has also been considered important in maintaining correct cell differentiation in the kidney.
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Ectopic expression of ephrin-B1 causes cell:cell dissociation of Xenopus blastomeres (Jones et al., 1998), and, in the intestinal crypts of the mammalian gut, EphB/ephrin-B signaling maintains correct Paneth cell compartmentalization by regulating differential cell:cell adhesion (Solanas et al., 2011).
These findings show that CEP57 function is crucial for maintaining correct chromosomal number during cell division.
The fact that freshwater fish blood has maintained a sea-water like ionic condition is precisely the point, as it demonstrates the necessity of maintaining correct extracellular ion concentrations for cell survival.
One of the most important protein complexes involved in maintaining correct RNA levels in eukaryotic cells is the exosome, a complex consisting almost exclusively of exoribonucleolytic proteins.
Two studies have shown that precise control of miR-34a expression in the beta cell is needed to maintain correct beta-cell function.
In contrast, paralogs in Clade 2 have a higher distribution in the Posttranslational modification and chaperone (O) and the Cell membrane biogenesis (M) categories, suggesting an increased need for maintaining correct protein folding and high membrane stability during rapid growth.
Integrins also play an important role in maintaining correct lymphocyte compartmentalization within the spleen, specifically by retaining marginal zone (MZ) B cells at the marginal zone [ 6].
The adhesion of cells within the extracellular matrix is an important component of maintaining correct multicellular structure, with dysfunction of this process associated with metastasis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com