Sentence examples for maintaining chromatin structures from inspiring English sources

Long terminal repeats (LTRs), such as Ty1-copia and Ty3-gypsy retrotransposons, are enriched in pericentromeric regions, playing important roles in maintaining chromatin structures and centromere functions and regulating gene expression in the host genomes [ 49].

Sir2 plays an essential role in gene silencing and in maintaining chromatin structure.

A comparison of the results of this study to the previous studies can be found in Table 2. Taken together, these data provide strong support for Oct4's role in maintaining chromatin structure in mESC via regulation of and interaction with a unique constellation of PcG and TrxG complexes.

Given the increase in H4K16ac on nascent chromatin, we sought to determine whether Hdacs1,2 play a role in maintaining chromatin structure during replication.

Components of the DNA replication machinery play crucial roles in maintaining chromatin structure through cell division and thus are pivotal for the regulation of pluripotency.

Knockdown of NCOR1 and SMRT increased acetylated H4K5 and caused DNA damage, indicating that the HDAC3/NCOR/SMRT axis may be critical for maintaining chromatin structure and genomic stability.

Finally, the possibility also exists that the deletion may alter the interaction of AtCTF7 with other proteins, either directly or indirectly involved in maintaining chromatin structure.

AML1 and fusion protein occupancy at distal sites may be important for maintaining chromatin structure and for scaffolding protein-protein interactions.

Intricate protein networks are involved in maintaining chromatin structure and function, and DNA can adopt distinct secondary structures besides the standard B-DNA helix;[ 1] this adds to the structural repertoire controlling the functionality of chromatin.

One such histone mark critical for maintaining chromatin structure is acetylated lysine 16 of histone H4 (acH4K16), a modification that can disrupt higher order chromatin organization and convert it into a more 'relaxed' configuration.

This observation is consistent with previous reports [ 5, 26] and transcriptions of some of these antisense RNAs are suggested to be a part of processes to maintain chromatin structures for subsequent gene regulation [ 27].