Sentence examples for maintaining chromatin structure from inspiring English sources

Sir2 plays an essential role in gene silencing and in maintaining chromatin structure.

A comparison of the results of this study to the previous studies can be found in Table 2. Taken together, these data provide strong support for Oct4's role in maintaining chromatin structure in mESC via regulation of and interaction with a unique constellation of PcG and TrxG complexes.

Components of the DNA replication machinery play crucial roles in maintaining chromatin structure through cell division and thus are pivotal for the regulation of pluripotency.

Finally, the possibility also exists that the deletion may alter the interaction of AtCTF7 with other proteins, either directly or indirectly involved in maintaining chromatin structure.

Given the increase in H4K16ac on nascent chromatin, we sought to determine whether Hdacs1,2 play a role in maintaining chromatin structure during replication.

AML1 and fusion protein occupancy at distal sites may be important for maintaining chromatin structure and for scaffolding protein-protein interactions.

Long terminal repeats (LTRs), such as Ty1-copia and Ty3-gypsy retrotransposons, are enriched in pericentromeric regions, playing important roles in maintaining chromatin structures and centromere functions and regulating gene expression in the host genomes [ 49].

Smolle, M. et al. Chromatin remodelers Isw1 and Chd1 maintain chromatin structure during transcription by preventing histone exchange.

To further complicate matters, however, PARylation is not only involved in stripping histones from DNA but also has been shown to be needed to maintain chromatin structure.

In addition to functioning in the DDR, and potentially acting to maintain chromatin structure, CHD4 has also been shown to contribute to the control of cell cycle progression.

Smolle et al. review two recent papers that show how the Set2-mediated methylation of H3K36 maintains chromatin structure by limiting histone dynamics over gene bodies, either by recruiting chromatin remodelers that preserve ordered nucleosomal distribution or by lowering the binding affinity of histone chaperones for histones, preventing their removal.