Sentence examples for maintaining cellular iron from inspiring English sources

The FXN gene encodes Frataxin, a mitochondrial protein involved in maintaining cellular iron homeostasis [12].

We further showed that NCOA4-mediated ferritinophagy is important for maintaining cellular iron homeostasis.

IRP1 is responsible for cytosolic iron concentrations and can post-transcriptionally regulate the expression of iron metabolism genes to maintain cellular iron homeostasis (Rouault, 2006).

Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are two cytosolic proteins that maintain cellular iron homeostasis by binding to RNA stem loops known as iron responsive elements (IREs) that are found in the untranslated regions of target mRNAs that encode proteins involved in iron metabolism.

DFO treatment decreased the expression of ferroportin and ferritin in SK-Mel-5 cells, as one would expect for a cell striving to maintain cellular iron levels.

Thus, the transferrin receptor maintains cellular iron homeostasis.

The IRE IRP system was initially defined as a relatively simple and ubiquitous post-transcriptional regulatory circuit that maintains cellular iron homoeostasis in vertebrates by orchestrating co-ordinated iron uptake by TfR1 and storage in ferritin.

Protein protein interactions (PPIs) are vital to maintaining cellular homeostasis.

Aquaporins (AQPs) are primarily involved in maintaining cellular water homeostasis.

Autophagy is of great significance in maintaining cellular homeostasis.

GRP94 plays an important role in maintaining cellular homeostasis.