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Together, the respiratory epithelium of conducting airways plays a critical role in pulmonary homeostasis, maintaining barrier function and sterility.
The integrity of the intestinal epithelium is essential for maintaining barrier function, nutrient uptake, metabolic homeostasis, and hence, organismal health and survival.
There is evidence that nonneuronal acetylcholine plays a role in sensation, cell-cell signaling, proliferation, and cell growth as well as maintaining barrier function [ 82].
Measurable changes in tight junction protein expression or localization that are predicted to play a key role in maintaining barrier function are typically more unpredictable.
The intestinal epithelium plays a crucial role in maintaining barrier function and immune homeostasis, a failure of which results in disease.
Like the BBB, the tight junctions at the apical layer of the epithelial cells are the structural basis of the BCSFB, which are essential to maintaining barrier function of the BCSFB, due to the naturally leaky and fenestrated endothelium [ 26].
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Thus, inhibition of FAK relocation might also contribute to the ability of FX06 to maintain barrier function.
Hence, tight regulation of NF-κB activity is critical in the intestinal mucosa in order to maintain barrier function during injury.
22, 25 Therefore, to investigate whether preservation of barrier integrity during seizures contributes to seizure resistance we used both pharmacologic and genetic strategies to maintain barrier function by inhibiting tPA-mediated PDGFR α signaling.
It must remain tightly balanced to allow nutrient absorption, but maintain barrier function and immune homoeostasis, a failure of which results in chronic infection or debilitating inflammatory bowel disease (IBD).
Further work will establish the precise mechanism by which GPA33 acts to maintain barrier function and protect against disease, although the cumulative evidence to date points to a role in cell-cell adhesion.
More suggestions(12)
maintaining brain function
maintaining protein function
maintaining ecosystem function
maintaining muscle function
maintaining barrier structure
maintaining barrier polarity
maintaining barrier immunity
maintaining cell function
maintaining organ function
maintaining barrier homeostasis
maintaining family function
maintaining memory function
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CEO of Professional Science Editing for Scientists @ prosciediting.com