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Cikala and colleagues proposed that Jmjd6 might possess an AT-hook DNA binding domain just C-terminal of the JmjC domain, which might allow binding of the protein to DNA [30] though structural predictions suggest maintaining a functional AT-hook whilst maintaining catalytic function is unlikely.
In a way, we don't deserve saving – we've been willing to forget every lesson history could have taught us about maintaining a functional, sustainable civil society.
SIVAS: We are seeing a shift toward valuing extractive resource use over maintaining a functional and productive ocean ecosystem.
Thus, antioxidants may selectively protect endothelial cells from Axitinib by decreasing systemic toxicity and maintaining a functional vascularization necessary for efficient delivery of chemotherapeutic drugs within the tumor mass.
Since the mutants originate from a directed evolution experiment and are functional, the data provide an evolutionary snapshot of how a protein structure can respond to mutations while maintaining a functional molecular architecture.
Ensuring proper protein folding by molecular chaperone networks thus represents the first level of maintaining a functional proteostasis network.
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Nonetheless, it maintains a functional flagellar basal body which actively exports fT3SS specific substrate proteins37.
How would we maintain a functional relationship with Moscow without condoning the further strangulation of democracy in Russia?
If proteins do misfold, they must be cleared to maintain a functional and healthy proteome.
Mitochondria are highly dynamic and undergo fission and fusion to maintain a functional mitochondrial network, which drives cellular metabolism5.
The monophysites, however, steadfastly resisted Sergius' indoctrination because he continued to maintain a functional humanity in Christ.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com