Sentence examples for maintaining a differentiated from inspiring English sources

These results suggest that a normal level of serotonin is critical for maintaining a differentiated brain response to threatening face emotions.

The use of biodegradable microcarriers as initial supports for tissue engineering has been demonstrated to be advantageous for maintaining a differentiated cell phenotype; the high surface area also allows rapid cell expansion.

We conclude that the miR-143/145 gene is necessary for maintaining a differentiated SMC phenotype in the adult.

However, they are consistent with the in vitro data that Sox6 is involved in promoting or maintaining a differentiated luminal phenotype, a corollary of which is that it blocks stem cell behaviour (transplantation).

Although the exact function of GSDMB remains unclear, members of the gasdermin-domain containing family have roles in epithelial cell apoptosis and in maintaining a differentiated state of epithelial cells [ 20].

Our findings suggest that a major role for BAP1 in this setting is to regulate transcriptional programs involved in maintaining a differentiated melanocytic phenotype and that loss of BAP1 triggers a loss of cell identity characterized by a primitive, stem-like phenotype.

The requirement for continuous regulation to maintain a differentiated phenotype was postulated previously.

Second, they proved that HOXD10, a homeobox transcription factor that promotes or maintains a differentiated phenotype in epithelial cells, is a target of miR-10b.

Explants of tracheas from hamsters were cultured in either a chemically defined minimal essential medium, which maintains a differentiated epithelium, or a nutritionally complex medium, which encourages the development of squamous metaplasia.

Therefore, in order to reinforce the concept that saffron-derived compounds maintain a differentiated state of prostate cancer cells, we analyzed the immunohistochemistry expression of proteases involved in the migratory and invasive properties of PCa.

For example, sinusoidal endothelial cells were able to maintain a differentiated phenotype when cultured on ECM derived from the liver but not on ECM derived from the small intestine or bladder [ 4].