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The PTO system comprised of commercially available off-the-shelf components and a design that can be manufactured and maintained with standard protocols [21].
CHO cells were obtained from ATCC and maintained with standard culture conditions (DMEM, 10s% FBS, 1× Penicillin-Streptomycin, 37°C, 5% CO2).
All strains were maintained with standard procedures and raised at 20°C [ 26].
Routine target concentrations >2 mg/L are maintained with standard dosing (1 g IV 8-hourly).
Interestingly in this study, routinely targeted meropenem plasma concentrations (>2 mg/L) were maintained with standard dosing, both in ECMO patients on RRT and those with preserved renal function.
It is of note that the pharmacological-treated dogs fed with IMMD dietary regimen recovered their condition, only basing on clinical observation, in a higher percentage if compared with those animals maintained with standard diet (65%% vs. 50%%) at the end of the study.
Similar(54)
Mice were group-housed in a colony maintained with a standard 12 h light/dark cycle and given food and water ad libitum.
It is also important to mention that low levels of disease activity could be achieved and maintained with a standard infliximab dosage of 3 mg/kg and that dosage increases were transient in a majority of patients.
Thirty male mice (9 weeks old; ∼25 35 g body weight) were housed at the Animal Institution in Showa University in acrylic cages (eight mice per cage) at 23°C, and maintained with a standard 12-hour light/dark cycle with optimum humidity and temperature control.
With proper dimensioning of the microfluidic channels, the flow loss through the nanoflow valve was less than 18% and flow stability could be maintained with a relative standard deviation (RSD) <1.5%.
The mice were maintained with water and standard mouse chow ad libidum that is used in protocols approved by the University's Animal Studies Committee.
Related(15)
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