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We then evaluated whether the response was maintained with continued exposure to the organophosphates.
In the original abatacept group, improvements in disease activity achieved by the end of the double-blind period were maintained with continued abatacept treatment through the LTE.
The improvement in mood was observed on day 30 and was maintained with continued treatment for six 42 and 36 months.
Clinically meaningful improvements in pruritus, night sweats, and bone pain were observed within 4 weeks of the initiation of therapy and maintained with continued treatment.
The PDE-5 inhibitor, vardenafil, is characterized by a rapid onset of action, increased duration of erection, high rates of first-dose success and reliable efficacy that can be maintained with continued use.
21, 22 Vardenafil is a selective PDE-5 inhibitor, with a profile characterized by rapid onset of action, increased duration of erection, high rates of first-dose success and reliable efficacy that can be maintained with continued use.
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One of the potential benefits to varenicline use as demonstrated in the trial by Tonstad et al 17 is that the drug appears to possess the potential to help patients maintain abstinence with continued use.
Additionally, longer-term trials are needed to determine whether the observed gains are maintained with or without continued intervention.
For the first one to three passages, cells grown in USSC growth mediumACF proliferate and maintain their morphology, but with continued passaging the cells form spherical cell aggregates.
8 After week 52, the open-label treat-to-target strategy was adapted based on response where study medication could be tapered, continued, intensified or maintained with the goal of achieving drug-free remission.
We next stopped treatment and ten days later 75%% of arthritic mice treated with both inhibitors either maintained or continued to ameliorate clinical signs (Fig. 5d).
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