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Vice versa, an environmental toxicant that inhibits a cellular pathway may need to do this continuously to exert developmental effects, i.e., an average toxic concentration (AUC) needs to be maintained to result in an average long-term inhibition.
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Hence, a threshold load would ultimately be reached and either maintained (survivors) or advance to result in host morbidity.
The evidence also clearly supports SDT's premise that an individual's intrinsic motivational tendencies usually require external support to result in maintained behaviour change, and that these tendencies are easily reversed by a non-supportive environment [ 38].
The remission rates for those not in full endoscopic and clinical remission were less than those achieved by the intention-to-treat populations as a whole, suggesting that full endoscopic and clinical remission at entry were more likely to result in maintained remission at 12 months.
On the other hand, for high sodium gluconate titer, high initial glucose concentration and continuous addition of neutralizer (NaOH) to maintain suitable environmental pH are considered to result in strong osmotic stress.
This is likely to be important for maintaining coordinated behaviour across species, and to result in quick and adaptive flock responses to food resources that are patchily distributed in space and time.
Poorly maintained instruments may result in poor tone, difficulty of playing, or the inability to play the instrument at all.
This not only provides a transparent way of structuring the model, which supports the analysis both conceptually and computationally, but also makes the model easier to maintain, resulting in local model refinements instead of global changes.
The introduction of such naive dams and their lambs into an experimental flock in which scrapie is maintained naturally resulted in transmission to both [ 22].
The expandable nail is also used in the treatment of humeral fractures, and several authors have described cases of failure of the device leading to deflation within the humerus and proximal migration or failure to maintain reduction, resulting in non-union [12, 42].
As the plosive portion of an affricate is released into the fricative portion, the high pressure buildup at the end of the closure would tend to create an intraoral pressure level that is too high to maintain voicing, resulting in a (partially) devoiced affricate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com