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Significant separation from placebo was observed from week 1 for both doses of quetiapine and was maintained through week 8 (Figure 2).
This increase was maintained through week 4 (P = 0.03).
Responses were maintained through week 24 and then started deteriorating.
Clinical benefit was maintained through Week 56 in all effectiveness parameters.
These benefits were achieved as early as week 10 and were generally maintained through week 54.
Additionally, patients receiving MVC had improved immunologic responses, and this advantage was maintained through week 240.
Similar(32)
RCTs on naïve patients [ 2- 4] observed that patients achieving an extended rapid virological response (eRVR), defined as negative HCV-RNA at week 8 maintained through to week 24 for BOC, and as negative HCV-RNA at week 4 maintained through to week 12 for TVR, obtained SVR in more than 90% of cases also reducing treatment duration to 24 and 28 weeks in TVR and BOC-based therapies respectively.
Albiglutide treatment produced a rapid effect on FPG; there was a steep decline from baseline up to week 2 and the reduced levels were maintained through to week 52.
The observed reduction in IOP with BRINZ/TIM-FC was evident after 4 weeks of treatment and was maintained through 8 weeks.
Our CCI data in Gli1-CreER T2 mice differ from these prior studies in that heritable labeling for Shh pathway activation was reduced in the cortical lesion area at 2 weeks postinjury, and this was maintained through 6 weeks.
26 Dapagliflozin 5 mg and 10 mg once daily added to pioglitazone ≥30 mg once daily resulted in statistically significant reductions in HbA1c after 24 weeks of therapy, which was maintained through 48 weeks of therapy, compared to placebo (−0.95% and −1.21% versus −0.54%).
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