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Expression of rabies virus G protein was stable and maintained through multiple rounds of in vitro passaging.
Epigenetic phenomena reflect alternative gene expression states that are maintained through multiple rounds of mitosis, and sometimes through meiosis.
Saturation binding repeated at intervals throughout the experimental period verified that the levels observed initially were maintained through multiple passages (up to 30), demonstrating the stable nature of α7-nAChR expression by this cell line.
In contrast with v-Src-transformed cells, TGF-β3 mRNA is up-regulated in QNR/v-srcts/ICN cells, once ICN stable expression is established, and is maintained through multiple cell passaging despite the presence of an active oncoprotein.
A laminated and variegated granular morphology, displaying alternating electron-dense and pervious layers resembling "bull's eyes," could be more clearly seen with NB "strains" that had been maintained through multiple serial passages in the presence of excess serum (5 10% FBS), as illustrated by thin section images of "nanons" shown in the bottom row of Figure 5 (Q T).
Is this single transcription site stably maintained through multiple generations?
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We found that while cultured cortical and spinal cord derived NSCs respond similarly to mitogens and are equally neuronogenic, they retain and maintain through multiple passages gene expression patterns indicative of the region from which they were isolated (e.g Emx2 and HoxD10).
We expect that this state is maintained through differentiation into multiple lineages.
In summary, we show that acinar cell differentiation, maintained through PTF1A, suppresses multiple oncogenic pathways associated with PDAC initiation and progression.
From these observations, we can hardly conclude that the multiple PDE1Cb genes were maintained through the acquisition of new enzyme functions.
But as Hobson and Leonard point out, patients are highly individual, each requiring an individual program of care drawn from multiple branches of learning and negotiated and maintained through extended interaction.
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