Sentence examples for maintained their pluripotency from inspiring English sources

The results of this study show that porcine iPSCs that were directly generated from ear skin fibroblasts, using lentiviral vector expressing human factors: POU5F1 (OCT4), NANOG, SOX2, C-MYC, KLF4, and LIN28, generated porcine iPSCs that had characteristics similar to those of naïve-like pluripotent stem cells and maintained their pluripotency and self-renewal by the LIF or BMP-4 mediated pathway.

For long-term culture, these hiPSCs maintained their pluripotency and normal karyotype.

Overall, these results showed that NT2 cells maintained their pluripotency, undifferentiated phenotype, and differentiation potential along expansion in the bioreactor.

When cultured for successive passages on Cultispher-S microcarriers, mESCs maintained their pluripotency, demonstrated by self-renewal, expression of pluripotency markers and the ability to undergo multi-lineage differentiation.

Subsequently it was found that mES cells placed in synthetic medium (N2B27) in the presence of LIF and BMP4 maintained their pluripotency, which demonstrated that BMP is the component in Serum responsible for inhibition of differentiation (Ying et al., 2003a).

With this new freezing thawing procedure, more than 90% of the cells survived, maintained their pluripotency, had normal karyotype and showed a good capacity to grow, without delays, after thawing.

The expansion of pluripotent cells (ESCs and iPSCs) under conditions that maintain their pluripotency is necessary to implement a cell therapy program.

Our results showed that levitation of ES cells at the highest employed acoustic pressure for 60 min does not modify gene expression and cells maintain their pluripotency.

When cells are isolated from the inner cell mass of the blastocyst, they can be massively expanded in the laboratory, while maintaining their pluripotency.

Studies involving scanning electron and fluorescence microscopy, histological observations and flow cytometer analysis of the constructs implied that the polygonal cells attached to and penetrated the pores, and proliferated well, while maintaining their pluripotency during the culture period for 28 days.

Recent studies have shown that mESCs and human ESCs (hESCs) maintain their pluripotency using different extrinsic factors.