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While initially Uber continued its pilot even in the face of regulatory objections, both the DMV and California's Attorney General's office said that Uber would face legal repercussions, including injunctive action, if they maintained the active service.
Treatment with PTP-1 mainthened the active form of Lck over time.
AKT and MAPK42/44 phosphorylation was diminished in the shRNAi clone under IGF-1 stimulation, whereas TC71wt and mock cells maintained the active phosphorylation status in both kinases.
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This result suggests that phosphorylation serves as a trigger for the activation process but is not essential to maintain the active state.
For example, RACK1 stabilizes the activity of protein phosphatase 2A (PP2A) [ 58, 59] and maintains the active conformation of PKCβII [ 42, 45, 60].
Deletion of the "LLWL" motif abrogated the proteolytic activity, indicating that the motif is critical for maintaining the active proteinase conformation.
Its mammalian ortholog, RACK1 was initially discovered as a receptor for activated protein C kinase (PKC) that functions to maintain the active conformation of PKC and to support its movement to target sites.
FRRs are typically activated (manually or automatically) within 15 min, in order to maintain the active power balance in the power system and the power exchange with neighbouring power system on its schedule.
The TSOs have to maintain the active power in balance in any operating condition.
Handoff management maintains the active connections for roaming mobile terminals as they change their points of attachment to the network.
Our results also reveal the significant loop residues in maintaining the active binding conformation in the HD32D228 model.
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