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The maintained progression through treatment completion is an essential time to prevent abandonment of therapy.
The reason why only a few of the control patients maintained progression during the course of the trial might be that, according to the protocol, the progression required for inclusion did not have to be proven by keratometry.
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Patients who maintained progression-free intervals longer than 24 months had a 5-year survival rate of about 90%.
Patients who maintained progression-free intervals longer than 2 years had a 5-year survival rate of approximately 90%, and the rate did not increase thereafter.
Regardless of the severity of arthritis in the inflamed joint or pharmacological treatment, we observed dramatic counterregulation in the contralateral hindlimb to maintain progression.
In addition, 79% of patients treated with abatacept with no progression at year 1 maintained no progression of structural damage at year 2, demonstrating a durable effect on radiographic outcomes with abatacept therapy.
The efficacy of treatments was evaluated in all patients who were allocated to induction treatment; response rate was recorded and follow-up for progression free survival (PFS) and overall survival (OS) was maintained till progression and death for all patients who completed the induction and concurrent treatment.
The CD169+ phenotype arises shortly after HIV-1 seroconversion, is maintained during progression to AIDS, and does not specifically occur during therapy failure, as suggested earlier [4].
For instance, in colon cancer, an additional copy of Chromosome 7 is not only observed in early pre-malignant polyps, but is faithfully maintained throughout progression to metastasis.
Maintenance therapy refers to therapy administered after the initial chemotherapy regimen and it is continued or maintained until progression.
The presence of RE in both fractions of primary disease, whereas RE-negativity was maintained during progression from primary to secondary disease.
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