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However, in contrast to residents with impaired cognition (no differences between intervention and control group), those with normal cognition in the intervention group may have maintained overall function (late life function and disability instrument total function, P=0.024) and lower limb function (late life function and disability instrument basic lower extremity, P=0.015).
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In 1995, Lemischka and coworkers showed that mice lacking function of either Flt3 or Kit maintained overall normal populations (Mackarehtschian et al., 1995).
Despite the significant role of molecular networks in determining an organism's adaptation to its environment, we still do not know how such inter- and intra-molecular interactions within networks change over time and contribute to an organism's evolvability while maintaining overall network functions.
These are usually expected to be less than one due to a predominantly purifying selective force maintaining overall protein structure and function over time.
We postulate that evolution of alternative proteins, such as the ALP1 proteins (Fig. 1), could enable parasites to regulate actin polymerization in a more streamlined mechanism, yet maintain the overall function of the complex.
In this context, the centrosome and microtubules play an important role in maintaining overall cell polarity and provide an architectural framework for several cell functions.
Health care providers and sexually active adults should recognize that as long as individuals maintain overall health, normal aging will not compromise sexual functioning[ 19].
Overall, pyrogallol helped to maintain overall quality attributes and reduced quality-related physiological and biochemical activities.
All proteins exhibited regions of strong conservation proving the importance of maintaining structural stability and overall function in these proteins.
In light of these findings, researchers concluded that a stable mood and overall function could be maintained during extended duration spaceflights, such as manned missions to Mars.
The overall function of aquaporins is to maintain cellular water homeostasis [28], [29].
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