HIV-1 manipulates cellular machineries such as cyclin dependent kinases (cdks) and their cyclin elements, to stimulate virus production and maintain latent infection.
These results suggest that this antigen could play an important role in the immune response that maintains latent infection, and could therefore, be a good candidate as a new subunit vaccine to prevent disease reactivation.
This passage — infused with the spirit of nineteenth century imperialism (and perhaps, as some maintain, latent racism) — is often ignored by defenders of Mill as an embarrassment (Parekh, 1994; Parekh, 1995; Mehta, 1999; Pitts, 2005).This is not to say that such Millian passages are without a defense.
SIV-negative cynomolgus macaques with latent TB have a <5% chance of undergoing reactivation and can maintain latent TB without reactivation for more than three years (unpublished data).
A particular feature of herpes viruses is their ability to establish and maintain latent infections wherein the virus genome circularizes and persists as an episome.
This suggests that miR-155 expression may actually benefit certain viruses, and one report has supported a role for miR-155 induction to maintain latent viral genomes through the negative regulation of an established miR-155 target, IKKε [43].
KSHV establishes and maintains latent infection in CD19+ B cells.
A common feature of herpes viruses is their ability to maintain latent infections during which no virus particles are produced.
Identification of LANA's interacting partners would provide new insights into the mechanisms LANA uses to maintain latent infection.
In conclusion, our meta-analysis strategy re-analyzed EBV-related tumor data sets and identified sets of meta-genes possibly involved in maintaining latent or switching to lytic cycles of EBV in NPC.
