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NRG maintained its biological activity after the microencapsulation process.
Horseradish peroxidase (HRP) activity assays showed that the protein immobilized on the plasma polymerized surfaces maintained its biological function for a much longer period of time compared to that on uncoated surfaces.
Furthermore, PDGF maintained its biological function throughout the electrospinning process, and when combined with the natural, chemotactic properties of Fb elicited dermal fibroblast migration that is functionally equivalent to a single 50 ng/mL dose of PDGF.
The immobilized Hb in the film maintained its biological activity, showing a surface-controlled process with the heterogeneous electron transfer rate constant (ks) of 1.83 s−1 and displayed the same features of a peroxidase in the electrocatalytic reduction of oxygen and hydrogen peroxide (H2O2).
We established that GLP-1 stored in a home freezer maintained its biological activity with respect to responses of glucose and pancreatic polypeptide.
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These results indicate the rABL is an excellent lipophilic anticancer drug carrier, and that it maintains its biological function.
Previous studies performed on mutations at Lys22 and Met21 residues, replaced by Dpn22 and Nle21, respectively, 10 did not reveal whether it is necessary to maintain the physical chemical properties to maintain its biological effect at the system.
The matrix demonstrated a release profile of BMP-7 in a sustained manner over 28 days, maintaining its biological activity.
Hence, special care was taken in choosing a suitable covalent binding procedure for functionalizing the aptamer on nanoparticle surface with effective binding by maintaining its biological activity (Janas and Janas 2011).
To improve the nuclease resistance of siRNA while reducing its induction of an innate immune response and maintaining its biological activity for possible therapeutic application, we designed and synthesized a series of double short hairpin RNAs (dshRNAs).
In order to alleviate this issue, we are now synthesizing various novel derivatives directly from deoxygedunin that possess better water solubility while maintaining its biological efficacy.
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